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Whole-body Iron Loss In Normal Man Measured with a Gamma Spectrometer¹

Berkeley, California

ABSTRACT

1. The average whole-body iron loss of twelve normal subjects was analyzed and explained by the change of distribution and a small amount of radioiron loss. The normal radioiron loss occurred mostly in the stool, mainly as blood loss and partly as the loss by exfoliation of mucous epithelia. A small quantity of radioiron loss in the urine due to the exfoliation of urogenital epithelia was suggested.

2. The average normal iron loss rate was 0.030% per day or 0.89 mg per day. This normal iron loss figure is in reasonable agreement with the daily amount of iron absorption.

3. The whole-body counter can detect a very minute amount of iron loss within a short period of time. This is the simplest and most accurate method for measuring the loss of body iron.

FOOTNOTES

¹ Donner Laboratory of Biophysics and Medical Physics University of California, Berkeley, California.