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Total Iron-Binding Capacity in Normal Pregnancy¹

Rochester, Minnesota

ABSTRACT

Using a chemical method of determining serum iron described by Ramsay and a method utilizing Fe⁵⁹ for determining total iron-binding capacity as described by Tauxe, we found that (1) serum-iron levels remained within normal limits with or without supplemental iron therapy during pregnancy; (2) the total iron-binding capacity exceeded normal starting in the sixth lunar month in the nontreated group and in the seventh lunar month in the treated group, and it decreased slightly in the latter toward term and had returned to normal in both groups by the fourth postpartum week; and (3) the fetal serum-iron levels were consistently higher than the maternal levels despite a consistently lower total iron-binding capacity in the fetus.

FOOTNOTES

¹ Read at the meeting of the Society of Nuclear Medicine, Montreal, Quebec, Canada, June 26 to 29, 1963.

² Section of Obstetrics and Gynecology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota.

³ Section of Clinical Pathology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota.

⁴ Section of Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota.