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New Haven, Connecticut
ABSTRACT
During a regional brain perfusion, albumin-131I added to the perfusing fluid rapidly decreased in activity and appeared in the peripheral circulation. When triethylene thiophosphoramide-S35 was present in the perfusing fluid, about 14 per cent appeared in the peripheral circulation within one minute. The concentration of radioactivity in the perfusing fluid, as a function of time, was described by an hyperbola. These results cast doubt on the efficacy of carrying regional brain perfusion beyond four or five minutes.
FOOTNOTES
1 Supported by USPHS Research Grants Nos. CA 6519 and HD 00411.
2 From the Departments of Radiology and Surgery, Yale University School of Medicine, New Haven, Connecticut.
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