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Statistical Evaluation of 125-I vs 131-I for Scanning Cold Lesions¹

Los Angeles

ABSTRACT

A statistical analysis of the relative delineation potentials of 125-I and 131-I for scanning a "cold" 3-cm-diameter lesion indicates that 125-I is better than 131-I, not only for a surface lesion, but also for lesions located as much as 2 cm below the surface. For a "cold" 3-cm-diameter lesion located at depths of 3 cm or greater, neither 125-I nor 131-I would delineate such a lesion under the specific conditions chosen for this study.

The application of the type of measurements made in this report and their statistical analysis is discussed in relation to the probability of detecting a lesion by ordinary scan techniques.

FOOTNOTES

¹ From the Department of Radiology, The University of California Center for the Health Sciences, Los Angeles, California 90024.