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The Journal of Nuclear Medicine Vol. 5 No. 11 883-886
© 1964 by Society of Nuclear Medicine
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Beta Radiation of Circulating Blood by an Implanted Shielded Y90 Source, A Preliminary Report of Technique

William H. Oldendorf, M.D., John T. Burroughs, M.D., Benedict Cassen, Ph.D. and Leonard W. Wetterau, Jr., B.S.1

Los Angeles

ABSTRACT

1. A technique is described in which chronic beta irradiation from Y90 of circulating blood is achieved in vivo.
2. Utilizing standard surgical techniques, a segment of the lower abdominal aorta of dogs is replaced by a flexible teflon arterial graft. A shield containing Y90 beads is placed about the graft. Irradiation of blood is achieved through the graft material.
3. After placement of the graft and shielded radioactive source, the animal's activities are not restricted.
4. Two dogs subjected to this final form of the technique tolerated the procedure well.

FOOTNOTES

1 From the Neurology Section (Dr. Oldendorf), Radioisotope Service (Mr. Wetterau) and Cardiac Surgery Service (Dr. Burroughs), Veterans Administration Center, Los Angeles, Dr. Cassen is from the Division of Nuclear Medicine, UCLA Center for the Health Sciences.




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