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Cerebral Blood Flow During External Cardiac Massage^1,2

Baltimore

ABSTRACT

(1) Cerebral blood flow was measured in anesthetized dogs by determining the rate of clearance of radioactive inert gases (Kr⁸⁵ and Xe¹³³) from the brain after injection into the internal carotid artery.

(2) External cardiac massage during cardiac arrest restored cerebral blood flow to approximately one-third of that measured during normal cardiac action in the same animals.

(3) In the anesthetized dog, over a pressure range from 15 to 150 mm Hg, cerebral blood flow increased in an approximately linear fashion as arterial pressure increased.

FOOTNOTES

¹ Supported in part by U.S.P.H.S. Grant No. HE-07682-01.

² Departments of Medicine, Surgery and Radiology, The Johns Hopkins University School of Medicine, Baltimore, Maryland.