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I¹³¹ Content in Ovarial and Other Tissues at Different Times After Oral Administration¹

Iowa City, Iowa

ABSTRACT

In addition to confirming the findings of others that the human ovary does not concentrate I¹³¹ when given as NaI, the great concentration in the fetal thyroid over that of the blood DAR has been demonstrated. The DAR of the fetal thyroid increases from about 75 to as much as 22,000 as the fetus develops from the third to the sixth month of gestation. It has also been demonstrated in one instance that I¹³¹ as T3 crossed the placenta and was concentrated loosely in the fetal thyroid with a DAR of about 8.5.

FOOTNOTES

¹ Supported in part by grants AT(11-1)291 from the Division of Biology and Medicine, U. S. Atomic Energy Commission.

² From the Radiation Research Laboratory, Department of Internal Medicine and Obstetrics and Gynecology, College of Medicine, State University of Iowa.

³ We wish to express our appreciation to Drs. W. C. Keettel, H.J.B. Manderson and others of the Obstetrics and Gynecology Department for their cooperation in providing the tissues.