HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) CME Activity An erratum has been published All Versions of this Article: jnumed.107.050195v1 49/8/1305    most recent Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Related articles in JNM Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Buck, A. K. Articles by Drzezga, A. Search for Related Content PubMed PubMed Citation Articles by Buck, A. K. Articles by Drzezga, A.

SPECT/CT^*

¹ Department of Nuclear Medicine, Technische Universität München, München, Germany; and ² Department of Radiology, Technische Universität München, München, Germany

Correspondence: For correspondence or reprints contact: Andreas K. Buck, Department of Nuclear Medicine, Technische Universität München, Ismaninger Strasse 22, D-81675 Munich, Germany. E-mail: andreas.buck{at}tum.de

In view of the commercial success of integrated PET/CT scanners, there is an increasing interest in comparable SPECT/CT systems. SPECT in combination with CT enables a direct correlation of anatomic information and functional information, resulting in better localization and definition of scintigraphic findings. Besides anatomic referencing, the added value of CT coregistration is based on the attenuation correction capabilities of CT. The number of clinical studies is limited, but pilot studies have indicated a higher specificity and a significant reduction in indeterminate findings. The superiority of SPECT/CT over planar imaging or SPECT has been demonstrated in bone scintigraphy, somatostatin receptor scintigraphy, parathyroid scintigraphy, and adrenal gland scintigraphy. Also, rates of detection of sentinel nodes by biopsy can be increased with SPECT/CT. This review highlights recent technical developments in integrated SPECT/CT systems and summarizes the current literature on potential clinical uses and future directions for SPECT/CT in cardiac, neurologic, and oncologic applications.

Key Words: scintigraphy • SPECT • CT • PET • hybrid imaging

^* NOTE: FOR CE CREDIT, YOU CAN ACCESS THIS ACTIVITY THROUGH THE SNM WEB SITE (http://www.snm.org/ce_online) THROUGH AUGUST 2009.

No potential conflict of interest relevant to this article was reported.

COPYRIGHT © 2008 by the Society of Nuclear Medicine, Inc.

Related articles in JNM:

This Month in JNM

JNM 2008 49: 11A-12A. [Full Text]  

This article has been cited by other articles:

				N. Aide, N. Heutte, J.-P. Rame, E. Rousseau, C. Loiseau, M. Henry-Amar, and S. Bardet Clinical Relevance of Single-Photon Emission Computed Tomography/Computed Tomography of the Neck and Thorax in Postablation 131I Scintigraphy for Thyroid Cancer J. Clin. Endocrinol. Metab., June 1, 2009; 94(6): 2075 - 2084. [Abstract] [Full Text] [PDF]

				P. Knoll, G. Krotla, K. Koriska, M. Rodriques, and S. Mirzaei SPECT/CT J. Nucl. Med., June 1, 2009; 50(6): 1009 - 1009. [Full Text] [PDF]

				A. K. Buck, S. G. Nekolla, S. I. Ziegler, and A. Drzezga Reply: SPECT/CT J. Nucl. Med., June 1, 2009; 50(6): 1009 - 1010. [Full Text] [PDF]

				B. L. Judson and A. R. Shaha Nuclear Imaging and Minimally Invasive Surgery in the Management of Hyperparathyroidism J. Nucl. Med., November 1, 2008; 49(11): 1813 - 1818. [Abstract] [Full Text] [PDF]