HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Figures Only Full Text Full Text (PDF) CME Activity Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Nichol, C. Articles by Kim, E. E. Search for Related Content PubMed PubMed Citation Articles by Nichol, C. Articles by Kim, E. E.

Molecular Imaging and Gene Therapy*

Department of Nuclear Medicine, The University of Texas M.D. Anderson Cancer Center, Houston, Texas

Molecular imaging is an emerging field of study that deals with imaging of disease on a cellular or genetic level rather than on a gross level. Recent advances in this field show promise, particularly in the imaging of gene expression. This article reviews the use of nuclear medicine, magnetic resonance, and optic imaging to visualize gene expression. A review is presented of current in vitro assays for protein and gene expression and the translation of these methods into the radiologic sciences. The merging fields of molecular biology, molecular medicine, and imaging modalities may provide the means to screen active drugs in vivo, image molecular processes, and diagnose disease at a presymptomatic stage.

Key Words: gene therapy • imaging • nuclear medicine • molecular medicine

This article has been cited by other articles:

				M. Paturneau-Jouas, E. Parzy, G. Vidal, P. G. Carlier, C. Wary, J.-T. Vilquin, E. de Kerviler, K. Schwartz, and A. Leroy-Willig Electrotransfer at MR Imaging: Tool for Optimization of Gene Transfer Protocols--Feasibility Study in Mice Radiology, September 1, 2003; 228(3): 768 - 775. [Abstract] [Full Text] [PDF]

				T. F. Massoud and S. S. Gambhir Molecular imaging in living subjects: seeing fundamental biological processes in a new light Genes & Dev., March 1, 2003; 17(5): 545 - 580. [Full Text] [PDF]