| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | RSS | TABLE OF CONTENTS |
|
|
|
||||||||
|
||||||||||
CLINICAL INVESTIGATIONS |
Department of Molecular and Medical Pharmacology, Ahmanson Biological Imaging Clinic/Nuclear Medicine, University of California, Los Angeles, School of Medicine, Los Angeles; and Northern California PET Imaging Center, Sacramento, California
Correct staging is important in selecting the appropriate treatment for lymphoma patients. PET imaging with 18F-FDG is useful for staging of lymphoma as well as for monitoring of therapy. However, to our knowledge, the clinical impact of PET on staging and management of lymphoma patients has not been reported. Methods: Standardized questionnaires were mailed to referring physicians asking them whether and how the results of PET imaging had influenced clinical staging and management of the disease in their patients. Management changes, when present, were classified as intermodality (e.g., medical to surgical, surgical to radiation, medical to no treatment) or intramodality (e.g., altered medical, surgical, or radiotherapy approach). Results: The referring physicians returned 52 of 108 questionnaires (48.1%). Physicians indicated that PET led to a change in the clinical stage in 44% of patients: 21% were upstaged and 23% were downstaged. Findings of the PET examination resulted in intermodality changes in management in 42% of patients, in intramodality changes in 10%, and in a combination of the management changes in 10%. Other, not further specified, treatment changes were reported in 6% of patients. PET did not result in any management changes in only 32% of patients. Conclusion: This survey-based study of referring physicians indicates that FDG PET has a major impact on the management of lymphoma patients, contributing to changes in clinical stage in 44% and changes in treatment in >60% of cases.
Key Words: lymphoma • 18F-FDG • PET • patient management
This article has been cited by other articles:
|
|
 |
|
  C. G. Cronin, R. Swords, M. T. Truong, C. Viswanathan, E. Rohren, F. J. Giles, M. O'Dwyer, and J. F. Bruzzi Clinical Utility of PET/CT in Lymphoma Am. J. Roentgenol., January 1, 2010; 194(1): W91 - W103. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Luigi Zinzani, V. Stefoni, M. Tani, S. Fanti, G. Musuraca, P. Castellucci, E. Marchi, M. Fina, V. Ambrosini, C. Pellegrini, et al. Role of [18F]Fluorodeoxyglucose Positron Emission Tomography Scan in the Follow-Up of Lymphoma J. Clin. Oncol., April 10, 2009; 27(11): 1781 - 1787. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Montravers, K. Kerrou, V. Nataf, V. Huchet, J.-P. Lotz, P. Ruszniewski, P. Rougier, F. Duron, P. Bouchard, J.-D. Grange, et al. Impact of Fluorodihydroxyphenylalanine-(18F) Positron Emission Tomography on Management of Adult Patients with Documented or Occult Digestive Endocrine Tumors J. Clin. Endocrinol. Metab., April 1, 2009; 94(4): 1295 - 1301. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. E. Hillner, D. Liu, R. E. Coleman, A. F. Shields, I. F. Gareen, L. Hanna, S. H. Stine, and B. A. Siegel The National Oncologic PET Registry (NOPR): Design and Analysis Plan J. Nucl. Med., November 1, 2007; 48(11): 1901 - 1908. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J. Lindsay, B. A. Siegel, S. R. Tunis, B. E. Hillner, A. F. Shields, B. P. Carey, and R. E. Coleman The National Oncologic PET Registry: Expanded Medicare Coverage for PET Under Coverage with Evidence Development Am. J. Roentgenol., April 1, 2007; 188(4): 1109 - 1113. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Hadithi, M. Mallant, J. Oudejans, J.-H. T.M. van Waesberghe, C. J. Mulder, and E. F.I. Comans 18F-FDG PET Versus CT for the Detection of Enteropathy-Associated T-Cell Lymphoma in Refractory Celiac Disease J. Nucl. Med., October 1, 2006; 47(10): 1622 - 1627. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. S. Jhanwar and D. J. Straus The Role of PET in Lymphoma J. Nucl. Med., August 1, 2006; 47(8): 1326 - 1334. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Y. Tsai, A. Taur, L. Espinosa, A. Quon, D. Johnson, S. Dick, S. Chow, R. Advani, R. Warnke, S. Kohler, et al. Staging accuracy in mycosis fungoides and sezary syndrome using integrated positron emission tomography and computed tomography. Arch Dermatol, May 1, 2006; 142(5): 577 - 584. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Schoder, A. Noy, M. Gonen, L. Weng, D. Green, Y. E. Erdi, S. M. Larson, and H. W.D. Yeung Intensity of 18Fluorodeoxyglucose Uptake in Positron Emission Tomography Distinguishes Between Indolent and Aggressive Non-Hodgkin's Lymphoma J. Clin. Oncol., July 20, 2005; 23(21): 4643 - 4651. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. E. Hillner, R. Tunuguntla, and M. Fratkin Clinical Decisions Associated With Positron Emission Tomography in a Prospective Cohort of Patients With Suspected or Known Cancer at One United States Center J. Clin. Oncol., October 15, 2004; 22(20): 4147 - 4156. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. E. Thompson and C. B. Thompson Putting the Rap on Akt J. Clin. Oncol., October 15, 2004; 22(20): 4217 - 4226. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. B. Eubank, D. Mankoff, M. Bhattacharya, J. Gralow, H. Linden, G. Ellis, S. Lindsley, M. Austin-Seymour, and R. Livingston Impact of FDG PET on Defining the Extent of Disease and on the Treatment of Patients with Recurrent or Metastatic Breast Cancer Am. J. Roentgenol., August 1, 2004; 183(2): 479 - 486. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Agress Jr and B. Z. Cooper Detection of Clinically Unexpected Malignant and Premalignant Tumors with Whole-Body FDG PET: Histopathologic Comparison Radiology, February 1, 2004; 230(2): 417 - 422. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M Hoffmann, H Vogelsang, K Kletter, G Zettinig, A Chott, and M Raderer 18F-fluoro-deoxy-glucose positron emission tomography (18F-FDG-PET) for assessment of enteropathy-type T cell lymphoma Gut, March 1, 2003; 52(3): 347 - 351. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Seltzer, C. S. Yap, D. H. Silverman, J. Meta, C. Schiepers, M. E. Phelps, S. S. Gambhir, J. Rao, P. E. Valk, and J. Czernin The Impact of PET on the Management of Lung Cancer: The Referring Physician's Perspective J. Nucl. Med., June 1, 2002; 43(6): 752 - 756. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | RSS | TABLE OF CONTENTS |
| JOURNAL OF NUCLEAR MEDICINE TECHNOLOGY | THE JOURNAL OF NUCLEAR MEDICINE |
