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Multiple Myeloma Evaluated with ²⁰¹Tl Scintigraphy Compared with Bone Scintigraphy

Departments of Radiology and Internal Medicine, Toyama Medical and Pharmaceutical University, Toyama
Department of Nuclear Medicine, Kanazawa University, Kanazawa
Department of Radiology, Asahikawa Medical University, Asahikawa
Department of Internal Medicine, Himi City Hospital, Himi, Japan
Nuclear Medicine Service, Veterans Affairs Palo Alto Health Care System, Palo Alto
Department of Radiology, Stanford University School of Medicine, Stanford, California

Correspondence: For correspondence or reprints contact: Naoto Watanabe, MD, Department of Radiology, Toyama Medical and Pharmaceutical University, Sugitani 2630, Toyama City, Japan 930-0194.

ABSTRACT

The purpose of this study was to investigate the clinical usefulness of ²⁰¹Tl chloride Scintigraphy in the diagnostic evaluation of 20 patients with multiple myeloma (19/20 patients) or extramedullary plasmacytoma (1/20 patients) in comparison with bone scintigraphy. Methods: Both ²⁰¹Tl and bone Scintigraphy were performed to obtain planar images on the same instrument. Results: ²⁰¹Tl scintigraphy showed increased uptake in 15 of 20 patients (75%) and was negative in 5 of 20 patients (25%). In addition, ²⁰¹Tl scintigraphy of multiple myeloma was more useful in detecting the lesions in 11 of 17 patients and less useful in 6 of 17 patients than bone scintigraphy. Conclusion: The combination of ²⁰¹Tl and bone scintigraphy, compared with bone scintigraphy alone, shows promise in more accurately diagnosing multiple myeloma.

Key Words: multiple myeloma • ²⁰¹Tl scintigraphy • bone scintigraphy

This article has been cited by other articles:

				E. J. C. Angtuaco, A. B. T. Fassas, R. Walker, R. Sethi, and B. Barlogie Multiple Myeloma: Clinical Review and Diagnostic Imaging Radiology, April 1, 2004; 231(1): 11 - 23. [Abstract] [Full Text] [PDF]