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Bremsstrahlung Radiation Exposure From Pure ß-Ray Emitters

Division of Nuclear Medicine, New York Hospital-Cornell Medical Center, New York, New York

Correspondence: For correspondence or reprints contact: Pat B. Zanzonico, PhD, Nuclear Medicine Service, Memorial Sloan-Kettering Cancer Center, 1275 York Ave., New York, NY 10021.

ABSTRACT

With increasing therapeutic use of radionuclides that emit relatively high-energy (>1 MeV) ß-rays and the production in vivo of bremsstrahlung sufficient for external imaging, the potential external radiation hazard warrants evaluation. Methods: The exposure from a patient administered ß-ray-emitting radionuclides has been calculated by extending the National Council on Radiation Protection and Measurement model of a point source in air to account for biologic elimination of activity, the probability of bremsstrahlung production in vivo and its mean energy and the absorption by the patient's body of the bremsstrahlung thus produced. To facilitate such calculations, a quantity called the "specific bremsstrahlung constant" in C/kg-cm²/MBq-h), _Br, was devised and calculated for several radionuclides. The specific bremsstrahlung constant is the bremsstrahlung exposure rate (in C/kg/h) in air at 1 cm from a 1 MBq ß-ray emitter of a specified maximum ß-ray energy and frequency of emission in a medium of a specified effective atomic number. Results: For pure ß-ray emitters, the retained activities at which patients can be released from medical confinement (i.e., below which the effective dose equivalent at 1 m will not exceed the maximum recommended value of 0.5 cSv for infrequently exposed members of the general public) are extremely large: on the order of hundreds of thousands to millions of megabecquerels. Conclusion: Radionuclide therapy with pure ß-ray emitters, even high-energy ß-ray emitters emitted in bone, does not require medical confinement of patients for radiation protection.

Key Words: bremsstrahlung • ß-ray emitters • release criteria

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