HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Leslie, W.D. Articles by Peterdy, A. E. Search for Related Content PubMed PubMed Citation Articles by Leslie, W.D. Articles by Peterdy, A. E.

Comparison of Motion Correction Algorithms for Cardiac SPECT

Department of Nuclear Medicine, St. Boniface General Hospital, University of Manitoba, Winnipeg, Canada

Correspondence: For correspondence or reprints contact: W.D. Leslie, Department of Intemal Medicine (C5121), St. Boniface General Hospital, 409 Tache Ave., Winnipeg, Canada R2H 2A6.

ABSTRACT

Patient motion remains a significant source of unsatisfactory cardiac SPECT examinations. The extent to which image recovery can be achieved with correction algorithms is unknown. Methods: Nine subjects who had completed motion-free redistribution ²⁰¹Tl cardiac SPECT subsequently underwent simultaneous dual-isotope (²⁰¹Tl/^99mTc) SPECT wtth a ^99mTc cutaneous point source, while the imaging table was subjected to predefined nonreturning y-translation movements. Cardiac reconstructions, marker reconstructions and marker-compressed dynamic images were generated from the raw data after applying the following correction methods: diverging squares, cross-correlation of the cardiac data and cross-correlation of the marker. Results: Marker cross-correlation performed significantly better than all other methods with good-excellent results in all evaluations. This compared with good-excellent results in none of 27 for the raw data, in 13 of 27 for cardiac cross-correlation and in 7 of 27 for diverging squares (p < 10^–5). The superiority of the marker-based method was confirmed on analysis of bullseye difference maps and quantitation of residual motion in the point-source data. Conclusion: Motion artifacts can accurately be detected and corrected using cross-correlation of an external point-source. Furthermore, this technique provides useful independent information on the degree of image recovery.

Key Words: thallium-201 • SPECT • motion artifacts • myocardial perfusion

This article has been cited by other articles:

				N. Matsumoto, D. S. Berman, P. B. Kavanagh, J. Gerlach, S. W. Hayes, H. C. Lewin, J. D. Friedman, and G. Germano Quantitative Assessment of Motion Artifacts and Validation of a New Motion-Correction Program for Myocardial Perfusion SPECT J. Nucl. Med., May 1, 2001; 42(5): 687 - 694. [Abstract] [Full Text]