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False-Positive Somatostatin Receptor Scintigraphy Due to an Accessory Spleen

Nuclear Medicine, Surgery and Gastroenterology Departments, Bichat Hospital;; Gastroenterology Department, Villeneuve Saint Georges Hospital, Paris, France

Correspondence: For correspondence or reprints contact: Rachida Lebtahi, MD, Service de Médecine Nucléaire, Hôpital Bichat, 46 rue Henri Huchard, 75018, Paris, France.

ABSTRACT

A patient with previous left caudal pancreatectomy and splenectomy presented with Zollinger-Ellison syndrome. Abdominal CT and endoscopic ultrasonography revealed a mass in the splenic area. Somatostatin receptor scintigraphy showed a nodular increase of the uptake corresponding to the lesion detected with conventional imaging. A second laparotomy was performed and the mass was resected. Histological analysis showed that the nodular lesion was an accessory spleen. Since physiologic uptake of ¹¹¹In-pentetreotide is seen in the spleen, an accessory spleen mimicking a tumor, specially after previous splenectomy, may result in false-positive somatostatin receptor scintigraphy.

Key Words: somatostatin receptor scintigraphy • gastroenteropancreatic tumors • accessory spleen

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