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The Journal of Nuclear Medicine Vol. 38 No. 12 1902-1906
© 1997 by Society of Nuclear Medicine
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Limitations of Dual-Photopeak Window Scatter Correction for Brain Imaging

Robert E. Zimmerman, Benjamin B. Williams, Karen H. Chan, Stephen C. Moore and Marie Foley Kijewski

Department of Radiology, Brigham and Women's Hospital; Nuclear Medicine Service, Brockton/West Roxbury Veterans Affairs Medical Center (SCM); Harvard Medical School, Boston, Massachusetts

Correspondence: For correspondence or reprints contact: Robert E. Zimmerman, MSEE, Department of Radiology, Brigham and Women's Hospital, 75 Francis Street, Boston MA 02115.

ABSTRACT

A method for performing scatter corrections that would directly use the photopeak information and would be straightforward for use in clinical practice would be attractive in SPECT imaging. The dual-photopeak window method may be such a method. It relates the scatter fraction to the ratio of the lower to the total parts of a split-photopeak window. We investigated the use of this scatter correction method on a dedicated brain camera. Methods: Calibration curves for the CeraspectTM, a dedicated brain imaging camera, were obtained for four split-window combinations using point sources in air and water. Simulations of the CeraspectTM calibration curves at several energy resolution values were obtained using a Monte Carlo simulation of the instrument. Results: The calibration curves, experimental and simulated, revealed an ambiguous and unstable relationship between lower-to-total ratio and scatter fraction. Conclusion: The unsatisfactory calibration curves can be attributed to the limited scatter produced in a brain-sized phantom during the calibration process and inherent stability problems in the calibration process. The dual-photopeak window method is not usable for small-field imaging systems and may even be unstable for larger-field systems.

Key Words: scatter correction • brain imaging






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Copyright © 1997 by the Society of Nuclear Medicine.