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Jod-Basedow Syndrome Following Oral Iodine and Radioiodinated-Antibody Administration

Nuclear Medicine Section, Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York

Correspondence: For correspondence or reprints contact: C. R. Divgi, MD, Nuclear Medicine Service Memorial Sloan-Kettering Cancer Canter, 1275 York Ave., NewYork, NY10021.

ABSTRACT

This is a case of thyrotoxicosis, presumably due to Jod-Basedow syndrome, after stable iodine ingestion for thyroid blockade in a patient with ovarian carcinoma having ¹³¹I-labeled monoclonal antibody imaging. With the increased use of radioiodinated antibodies, for therapy and imaging, this possible side effect of excess stable iodine adminstration should be noted, especially in patients with pre-existing goiter.

Key Words: hyperthyroidism • iodide ingestion • radioiodinated antibody

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