HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Morrison, S. C. Articles by O'Donnell, J. K. Search for Related Content PubMed PubMed Citation Articles by Morrison, S. C. Articles by O'Donnell, J. K.

Ifosfamide-Induced Alteration of Technetium-99m-DMSA Renal Parenchymal Imaging

Divisions of Pediatric Radiology and Nuclear Medicine, Department of Radiology, University Hospitals of Cleveland, Cleveland, Ohio

Correspondence: For correspondence or reprints contact: James K. O'Donnell, MD, Division of Nuclear Medicine, Department of Radioloogy, University Hospitals of Cleaveland, 11100 Euclid Ave., cleveland, OH.

ABSTRACT

Renal cortical imaging with ^99mTc-dimercaptosuccinic acid (DMSA) has become the imaging test of choice for the diagnosis of acute pyelonephritis. An unusual uptake pattern was observed in a child receiving chemotherapy for a bladder rhabdomyosarcoma. Chemotherapy from ifosfamide produces a specific pattern of injury to the renal tubule that alters uptake of DMSA.

Key Words: technetium-99m-DMSA • ifosfamide • renal tubular injury