HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Mizuno, H. Articles by Ishikawa, K. Search for Related Content PubMed PubMed Citation Articles by Mizuno, H. Articles by Ishikawa, K.

Continuous Ambulatory Radionuclide Monitoring of Left Ventricular Function: Effect of Body Position During Ergometer Exercise

Second Department of Internal Medicine, Kyorin University School of Medicine, Mitaka-city, Tokyo, Japan

Correspondence: For correspondence or reprints contact: Kyozo Ishikawa, MD, Second Department of Internal Medicine, Kyorin University of Medicine, 29-2 Shinkawa 6, Mitaka-city, Tokyo, 181, Japan.

ABSTRACT

We assessed the reliability of a continuous ambulatory radionuclide monitoring system (the VEST system, Capintec, Inc., Ramsey, NJ) for measurement of left ventricular performance during exercise in the upright and supine positions. Methods: Sixteen healthy male volunteers (aged 32–46 yr; mean age 37 ± 4 yr) were studied. All volunteers underwent ergometer exercise testing in both the upright and supine positions, and left ventricular performance was determined with the VEST system. Results: The resting heart rate, systolic blood pressure, pressure rate product, relative end-diastolic volume, relative end-systolic volume and left ventricular ejection fraction (LVEF) all showed no differences between the upright and supine positions. At peak exercise, the heart rate, systolic blood pressure and pressure rate product showed no diferences between the upright and supine positions. In the upright position at peak exercise the relative end-diastolic volume was increased (83% ± 9% to 91% ± 11%, p < 0.001); the relative end-systolic volume remained unchanged (34% ± 3% to 33% ± 15%), and LVEF was significantly increased from 58% ± 6% to 66% ± 11% (p < 0.01). In the supine position at peak exercise, the relative end-diastolic volume remained unchanged (85% ± 5 to 83% ± 7%), the relative end-systolic volume was increased (35% ± 5% to 43% ± 13%, p < 0.01), and LVEF was decreased from 58% ± 5% to 48% ± 17% (p < 0.01). These results indicated inferior data collection by the VEST system in the supine position. Conclusion: Since the detector of the VEST system may be too small, the data collection is impaired during exercise in the supine position by shifting the heart with deep respiration. The VEST system is very useful for determining left ventricular performance when applied in the sitting or upright position. However, in the supine position during exercise, the use of the VEST system should be avoided because it might indicate an artifactual deterioration of left ventricular performance.

Key Words: ambulatory radionuclide monitoring • left ventricular ejection fraction • exercise

This article has been cited by other articles:

				T. Akima, B. Takase, S. Kosuda, F. Ohsuzu, T. Kawai, M. Ishihara, and K. Akira Systemic Peripheral Vascular Resistance as a Determinant of Functional Cardiac Reserve in Response to Exercise in Patients With Heart Disease Angiology, September 1, 2007; 58(4): 463 - 471. [Abstract] [PDF]