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Utility of Technetium-99m-Sestamibi to Assess Osseous Tumor Spread

University Clinics of Maxillofacial Surgery, Pathology and Nuclear Medicine, Vienna, Austria

Correspondence: For correspondence or reprints contact: Thomas Leitha, MD, University Clinic Nuclear Medicine; Waehringer Guertel 18-20, A-1090 Vienna, Austria

ABSTRACT

We report the staging results and the surgical out come of a male patient with squamous-cell carcinoma in the floor of the mouth and a bone SPECT scan suggestive of local tumor infiltration of the mandible. AdditiOnal ^99mTc-sestamibi SPECT imaging of the primary tumor and superimposing of both studies excluded osseous tumor spread and less extensive surgery was performed. Pathohistological examination confirmed the scintigraphic results and indicated a nonspecific periostal reaction as the cause of the positive bone scan. Nevertheless, a high-resolution camera and careful superimposition of both studies is mandatory if the differential diagnosis of an osseous tumor spread of a malignant tumor in the floor of the mouth and possibly less extensive surgery is at stake.

Key Words: squamous-call carcinoma • technetium-99m-sestamibi • bone scintigraphy • SPECT

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