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Gallium-67-Citrate Scintigraphy of High-Grade T-Cell Non-Hodgkin's Lymphoma

Divisions of Nuclear Medicine and Hematology, Department of Internal Medicine, Divisions of Nuclear Medicine and MRI, Department of Radiology and Institute of Pathology, Karl-Franzens-University, Graz, Austria

Correspondence: For correspondence or reprints contact: Rainer W. Lipp, MD, Division of Nuclear Medicine, Department of Internal Medicine, Auenbruggerplatz 15, A-8036 Graz, Austria

ABSTRACT

Scintigraphy with ⁶⁷Ga-citrate indicated the transition of an orbital pseudotumor into a lymphoma by a distinct increase in ⁶⁷Ga avidity. The patient initially presented with a pseudo tumor in the right orbit that was verified by CT and MRI. It was caused by a chronic reactive lymphocytic inflammation extending from the lacrimal gland. At that time, scintigraphy was negative. Six and a half weeks later, the tumor had not responded to therapy and scintigraphy then showed a striking increase in gallium avidity. Consequently, the tumor was excised and histology ultimately revealed a high-grade non-Hodgkin's T-cell lymphoma.

Key Words: gallium-67-citrate • scintigraphy • orbital pseudotumor • non-Hodgkin's lymphoma