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Focal Accumulation of Iodine-123-BMIPP in Liposarcoma of the Thigh

Department of Radiology, Tottori University Faculty of Medicine, Nishimachi, Yonago, Japan

Correspondence: For correspondence or reprints contact: Yuji Suto, MD, Department of Radiology, Tottori University Faculty of Medicine, 36-1 Nishimachi, Yonago 683, Japan.

ABSTRACT

Findings for focal accumulation of ¹²³I-15-(p-iodophenyl)-3-R,S-methylpentadecanoic acid ([¹²³I]BMIPP) in a patient with liposarcoma of the thigh are presented. Iodine-123-BMIPP accumulated heterogeneously in the liposarcoma. The region with marked accumulation of [¹²³I]BMIPP was diagnosed as mixoid liposarcoma. The region with little accumulation of [¹²³I]BMIPP was diagnosed as well-differentiated liposarcoma. Differences in the accumulation of [¹²³I]BMIPP may reflect differences in fatty acid metabolism between histopathological types of liposarcoma.

Key Words: iodine-123-BMIPP • liposarcoma • fatty acid metabolism • tumor imaging