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Technetium-99m-Methoxyisobutylisonitrile in Localization of Ectopic Parathyroid Adenoma

Departments of Nuclear Medicine, Endocrinology, Surgery and Pathology, Hospital de Sant Pau, Barcelona, Spain

Correspondence: For correspondence or reprints contact: Lluis Berná, MD, Nuclear Medicine Unit, Hospital de Sant Pau, Pare Claret 167, 08025 Barcelona, Spain.

ABSTRACT

Preoperative localization of ectopic parathyroid lesions is crucial for the correct treatment of patients with primary hyperparathyroidism. Invasive and noninvasive procedures, including selective venography, ultrasound, CT and MRI provide limited sensitivity in the detection of ectopic lesions. We report three patients in whom ^99mTc-MIBI scintigraphy accurately detected ectopic parathyroid adenomas and was instrumental in the cure for these patients. Technetium-99m-MIBI scintigraphy provides a simple and accurate noninvasive test for the detection of ectopic parathyroid adenomas.

Key Words: primary hyperparathyroidism • ectopic parathyroid adenomas • technetium-99m-MIBI