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Comparative Radionuclide Imaging of Metastatic Insular Carcinoma of the Thyroid: Value of Technetium-99m-(V)DMSA

Departments of Nuclear Medicine, General Surgery and Pathology, Veterans General Hospital and National Yang-Ming University, Taipei, Taiwan

Correspondence: For correspondence or reprints contact: Tzu-Chen Yen, MD, Department of Nuclear Medicine, Veterans General Hospital-Taipei, Taiwan.

ABSTRACT

We report a case of metastatic insular carcinoma of the thyroid evaluated with ²⁰¹Tl, ^99mTc-MIBI, ^99mTc-(V)DMSA, ^99mTc-MDP and ¹³¹I whole-body scans, which were obtained after total thyroidectomy. For the majority of lesions detected in the skeleton and soft tissue, ¹³¹I images were generally available, although most were visualized easier with ^99mTc-(V)DMSA. Technetium-99m-MDP images were considered better than ^99mTc-(V)DMSA images in showing bone lesions but not soft-tissue lesions. Both ²⁰¹Tl and ^99mTc-MIBI scans provided sufficient advantage to exhibit neck and mediastinal metastases, but they did not surpass ^99mTc-(V)DMSA in detecting abdominal or bony lesions. In this patient with various metastases from insular carcinoma of the thyroid, ^99mTc-(V)DMSA seemed to be the tracer of choice for whole-body imaging.

Key Words: technetium-99m-(V)DMSA • insular carcinoma • thyroid

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				A. Machens, R. Hinze, C. Lautenschlager, and H. Dralle Multivariate Analysis of Clinicopathologic Parameters for the Insular Subtype of Differentiated Thyroid Carcinoma Arch Surg, August 1, 2001; 136(8): 941 - 944. [Abstract] [Full Text] [PDF]