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Differentiation of Infected from Noninfected Rapidly Progressive Neuropathic Osteoarthropathy

Department of Radiology, Indiana University School of Medicine, Indianapolis, Indiana

Correspondence: For correspondence or reprints contact: Donald S. Schauwecker, PhD, MD, Chief of Nuclear Medicine, Wishard Memorial Hospital, 1001 W. 10th St., Indianapolis, IN 46202.

ABSTRACT

Differentiation of infected from noninfected rapidly progressive neuropathic osteoarthropathy can be difficult in a combined bone/¹¹¹In-leukocyte study. We present two cases: one infected and one not infected. By examining the distribution of the ¹¹¹In leukocyte activity and the change in the lesion-to-background ratios from the 4-hr to the 24-hr image, it may be possible to determine if the rapidly progressive neuropathic osteoarthropathy is infected.

Key Words: indium-111-leukocytes • Charcot joints • osteomyelitis