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Metastatic Calcification of Multiple Visceral Organs in Non-Hodgkin's Lymphoma

Division of Nuclear Medicine, Departments of Radiology and Medicine, Mount Sinai Medical Center, New York, New York

Correspondence: For correspondence or reprints contact: Mordechai Lorberboym, MD, Division of Nuclear Medicine, Mount Sinai Medical Center, One Gustave L. Levy Pl., New York, NY 10029.

ABSTRACT

A patient with non-Hodgkin's lymphoma who developed acute hypercalcemia following chemotherapy was evaluated for skeletal metastases with whole-body bone scan. Although metastatic disease is an unlikely cause of hypercalcemia, considering the acutely rising serum calcium, the bone scan is useful in excluding multiple metastases as a cause. In addition, the study demonstrated metastatic calcification in multiple organs, including the pancreas which is uncommon, and the liver and spleen, which is rare.

Key Words: lymphoma • hypercalcemia • chemotherapy • metastatic calcification