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The Transition from Technegas to Pertechnegas

Department of Radiology, SUNY Health Science Center at Syracuse, Syracuse, New York

Correspondence: For correspondence or reprints contact: Dr. Ernest M. Scalzetti, MD, Dept. of Radiology, SUNY Health Science Center at Syracuse, 750 East Adams St, Syracuse, NY 13210.

ABSTRACT

We set out to determine the oxygen concentration of the argon-oxygen mixture in the technegas generator where technegas-like behavior changes to pertechnegas-like behavior which allows [^99mTc]pertechnetate to enter the solution. Methods: We prepared radioaerosols analogous to technegas and pertechnegas, with oxygen concentrations between 0% and 5%. They then were examined by thin-layer chromatography using saline as a solvent to measure the amount of [^99mTc]pertechnetate moving with the solvent front as a function of oxygen concentration. Results: The amount of mobile pertechnetate markedly increased when the radioaerosols were created in an atmosphere containing between 0.1% and 0.2% oxygen. The transition from technegas-like to pertechnegas-like behavior occurs when the oxygen-argon gas mixture contains lower concentrations of oxygen than those used in the preparation of pertechnegas. Conclusion: Argon intended for the preparation of technegas should contain no more than 0.1% oxygen.

Key Words: technegas • pertechnegas • technetium-99m-pertechnetate • argon • radioaerosol

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