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Department of Surgery, Nuclear Medicine and Nephrology, University Hospital St. Radboud, Nijmegen, The Netherlands
Correspondence: For correspondence or reprints contact: LG. van der Hem, MD, Department of Surgery, University Hospital Groningen, PO Box 30.001,9700 RB Groningen, The Netherlands.
ABSTRACT
We present two cases of compromised pancreatic graft perfusion on a routine 99mTc-HMPAO-scan. The radiopharmaceutical, hexamethylpropyleneamine oxime (HMPAO), labeled with 99mTc-provided high-quality scintigraphic images of transplanted pancreatic grafts. Findings were compared with subsequently performed x-ray digital subtraction angiographs. Pathological examination of both resected grafts revealed venous thrombosis in one case and graft pancreatitis in the other case of disturbed graft perfusion on a 99mTc-HMPAO-scan. While 99mTc-HMPAO scans of pancreatic grafts are not specific for early thrombosis, they seem to be a helpful tool in diagnosing pancreatic dysfunction in general, necessitating further diagnostic steps to elucidate the specific cause.
Key Words: pancreas transplantation technetium-99m-HMPAO scintigraphy early graft dysfunction
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