HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Barron, B. J. Articles by Lamki, L. Search for Related Content PubMed PubMed Citation Articles by Barron, B. J. Articles by Lamki, L.

Scintigraphic Manifestations of "Sternal Cupping"

Department of Radiology, Divisions of Nuclear Medicine and Pediatric Radiology, University of Texas Health Science Center at Houston, Houston, Texas

Correspondence: For correspondence or reprints contact: Bruce J. Barron, MD, 6431 Fannin, Suite 2.132, Department of Radiology, Houston, TX 77030.

ABSTRACT

Sternal abnormalities in sickle-cell disease have been documented by bone scintigraphy and radiography in patients with homozygous sickle-cell anemia, but not in patients with sickle-thalassemia. We present here two unusual cases of sternal abnormalities in complicated sickle-cell disease. One is an infant with radiographic findings of "sternal cupping" and transient hypo-ossification of the sternum and sickle-thalassemia. The other patient is also a male infant with unusual, persistent under-ossification of bone, in association with radiographic findings of "sternal cupping." The second patient also had a 4P-chromosomal defect (Wolf-Hirschhorn syndrome) in which sternal hypo-ossification was described.

Key Words: sternal cupping • sickle-cell thalassemia disease • hypo-ossification • sternal infarction