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Cholescintigraphy in the Diagnosis of Rotor Syndrome

Second Department of Pediatrics, University of Athens, First Department of Pediatric Surgery, A.P. Kyriakou Children's Hospital, Athens, Greece

Correspondence: For correspondence or reprints contact: Andrew M. Fretzayas, MD, 2nd Department of Pediatrics, University of Athens, A.P. Kyriakou Children's Hospital, Athens, 115 27, Greece.

ABSTRACT

In three patients with chronic conjugated hyperbilirubinemia who carried the diagnosis of Rotor syndrome, ^99mTc-HIDA cholescintigraphy was performed. In these patients, the liver was either not visualized or it was seen very faintly with slow liver uptake, persistent visualization of the cardiac blood pool and prominent kidney excretion. The present observation emphasizes the contribution of cholescintigraphy in the diagnosis of Rotor syndrome.

Key Words: Rotor syndrome • technetium-99m-HIDA cholescintigraphy • hyperbilirubinemia • Dubin-Johnson syndrome