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Dobutamine Myocardial Perfusion Imaging

Section of Cardiology, Baylor College of Medicine, Houston, Texas

Correspondence: For correspondence or reprints contact: Mario S. Verani, MD, Section of Cardiology, Baylor College of Medicine, 6536 Fannin F-905, Houston, TX 77030.

ABSTRACT

Dobutamine, a pharmacologic stressor, is useful for myocardial perfusion imaging in patients who cannot exercise. Patients with asthma or severe chronic obstructive pulmonary disease who are at risk for adverse effects from either dipyridamole or adenosine are prime candidates for dobutamine perfusion studies. Dobutamine is a predominant beta-1 agonist that increases heart rate, myocardial contractility and systolic blood pressure. The sensitivity and specificity of dobutamine myocardial perfusion imaging are comparable, for the most part, to those from perfusion studies using exercise, dipyridamole or adenosine.

Key Words: myocardial perfusion imaging • pharmacologic stress • dobutamine

FOOTNOTES

This paper was presented in part at the Annual Meeting of the Society of Nuclear Medicine on June 9, 1993, as part of a Continuing Medical Education Seminar organized by the Cardiovascular Council.

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