HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Maurea, S. Articles by Salvatore, M. Search for Related Content PubMed PubMed Citation Articles by Maurea, S. Articles by Salvatore, M.

Diagnostic Evaluation of Thyroid Involvement by Histiocytosis X

Nuclear Medicine Department, National Cancer Institute and Nuclear Medicine, Histopathology and Endocrinology Departments, University of Medicine Federico II, Napoli, Italy

Correspondence: For correspondence or reprints contact: Simone Maurea, MD, Via Raffaele De Cesare n. 7, 80132 Napoli, Italy.

ABSTRACT

We report the successful diagnosis of thyroid involvement by histiocytosis X due to accurate evaluation of nuclear medicine results. Methods: A total thyroidectomy specimen from our patient was initially suggestive of medullary thyroid carcinoma However, histologic reevaluation was performed on the basis of nuclear medicine findings which were incompatible with the original histologic diagnosis. Results: Immunohistochemical and light microscopy studies were performed to obtain the correct diagnosis. Diffuse thyroid involvement by histiocytosis X was demonstrated. Conclusion: Thyroid scintigraphy was helpful in successfully diagnosing thyroid involvement by histiocytosis X. Because tracer uptake is related to increased cellularity and metabolism, none of these tracers reported here is specific for defining histiocytosis X.

Key Words: histiocytosis X • thyroid • tumor-seeking agents

This article has been cited by other articles:

				L. Giovanella, L. Ceriani, S. Crippa, and L. Mazzucchelli Langherans Cell Histiocytosis of the Thyroid Gland Detected by 18FDG-PET/CT J. Clin. Endocrinol. Metab., August 1, 2007; 92(8): 2866 - 2867. [Full Text] [PDF]