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The Journal of Nuclear Medicine Vol. 35 No. 11 1802-1804
© 1994 by Society of Nuclear Medicine
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Transient Neurological Events During Dipyridamole Stress Test: An Arterial Steal Phenomenon?

David Schechter, Moshe Bocher, Yacov Berlatzky, Haim Anner, Zohar Argov, Gideon Beer, Yodphat Krausz, Mervyn S. Gotsman and Roland Chisin

Departments of Medical Biophysics and Nuclear Medicine, Cardiology, Vascular Surgery and Neurology, Hadassah University Hospital, Jerusalem, Israel

Correspondence: For correspondence or reprints contact: David Schechter, MD, Dept. of Medical Biophysics and Nuclear Medicine, Hadassah University Hospital, P.O. Box 12000, 91120 Jerusalem, Israel.

ABSTRACT

Dipyridamole-associated adverse neurological side effects have not been extensively described. We present two cases of dipyridamole-associated transient motor neurological events with no evidence of residual neurological deficits detected clinically or by head CT. The patients showed no evidence of significant extracranial (internal carotid) artery disease. We propose the presence of a regional cerebral perfusion disturbance due to an intracranial vascular steal phenomenon as the mechanism for the above side effects of dipyridamole.

Key Words: dipyridamole • exercise • neurological manifestations




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H. Ito, T. Kinoshita, Y. Tamura, I. Yokoyama, and H. Iida
Effect of Intravenous Dipyridamole on Cerebral Blood Flow in Humans : A PET Study
Stroke, August 1, 1999; 30(8): 1616 - 1620.
[Abstract] [Full Text] [PDF]




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