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Scintigraphic Detection of Osteomyelitis in Osteopetrosis

Department of Nuclear Medicine, Westfälische Wilhelms-Universität, Münster, Germany

Correspondence: For correspondence or reprints contact: Cornelia Puskás, MD, Klinik und Poliklinik für Nuklearmedizin, Westfälische Wilhelms-Universität Münster, Albert Schweitzer-Strasse 33, D-48149 Münster, Germany.

ABSTRACT

Methods and Results: The diagnosis of osteomyelitis in severe osteopetrosis may be difficult since altered bone architecture and fractures veil the typical radiographic signs of inflammation. We present a case of adult osteopetrosis with questionable clinical and radiographic signs of two osteomyelitic foci in the foot. Conclusion: Despite severe skeletal disease, the combination of skeletal and leukocyte scintigraphy suggested the diagnosis of infection.

Key Words: osteomyelitis • osteopetrosis • skeletal disease • leukocyte scintigraphy