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Renal Scintigraphy in Acute Scleroderma: Report of Three Cases

Departments of Nephro1ogy and Nuclear Medicine, Institute of Urology and Nephrology, University College London Medical School, London, United Kingdom

Correspondence: For correspondence or reprints contact: R.G. Woolfson, MD, MRCP, Department of Nephrology, Institute of Urology and Nephrology, 48 Riding House St., London W1N 8AA, U.K.

ABSTRACT

Scintigraphic findings in acute renal failure secondary to scleroderma are reported. In three patients, we have demonstrated severe reduction of renal perfusion with little or no parenchymal uptake of tracer and absent excretion. These findings are compatible with the known histological process of occlusive vasculopathy, and such scintigraphic findings at presentation may reflect a poor prognosis for renal recovery.