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Cerebral Vasodilatory Capacity Mapping Using Technetium-99m-DTPA-HSA SPECT and Acetazolamide in Moyamoya Disease

Departments of Radiology and Neurosurgery, Saitama Medical Center, Saitama Medical School, Saitama, Japan
Department of Radiology, University of Tokyo, Tokyo, Japan

Correspondence: For correspondence or reprints contact: Yusuke Inoue, MD, Dept of Radiology, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113, Japan.

ABSTRACT

A cerebral vasodilatory capacity map, consisting of a ^99mTc-DTPA-HSA SPECT image obtained after acetazolamide injection minus the baseline image, was produced in a patient with moyamoya disease. The map demonstrate diminished capacity in the posterior region of the right cerebral hemisphere. Subsequently, cerebral infarction occurred in the corresponding area. This observation suggests that regions of low vasodilatory capacity identified by cerebral vasodilatory capacity mapping may be at high risk of ischemic stroke.

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