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Cerebrovascular Accident Associated with Dipyridamole Thallium-201 Myocardial Imaging: Case Report

Department of Radiology, Division of Nuclear Medicine, University of Utah School of Medicine, Salt Lake City, Utah

Correspondence: For correspondence or reprints contact: Frederick L. Datz, MD, Director of Nuclear Medicine, Department of Radiology, University of Utah Medical Center, Salt Lake City, UT 84132.

ABSTRACT

A patient with known aortoiliac occlusive disease and hypertension suffered a cerebrovascular accident 6.5 min after the administration of intravenous dipyridamole during a ²⁰¹Tl myocardial study. Despite aminophylline administration, the patient developed a completed stroke. The mechanism most likely responsible for precipitating this patient's stroke is dipyridamole-induced vascular steal. Although dipyridamole-²⁰¹Tl myocardial imaging is relatively free of major complications, the morbidity and mortality associated with a cerebrovascular accident is significant. The possibility of precipitating a cerebrovascular accident during dipyridamole-²⁰¹Tl imaging should be considered in all patients with significant risk factors for stroke before performing a dipyridamole cardiac study.

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				H. Ito, T. Kinoshita, Y. Tamura, I. Yokoyama, and H. Iida Effect of Intravenous Dipyridamole on Cerebral Blood Flow in Humans : A PET Study Stroke, August 1, 1999; 30(8): 1616 - 1620. [Abstract] [Full Text] [PDF]