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Comparison of Technetium-99m-MIBI and Thallium-201-Chloride Uptake in Primary Thyroid Lymphoma

Nuclear Medicine Service and Lymphoma Service, Memorial Sloan-Kettering Cancer Center, New York, New York

Correspondence: For reprints contact: Andrew M. Scott, FRACP, Nuclear Medicine Service, Memorial Sloan-Kettering Cancer Center, 1275 York Ave., New York, NY 10021.

ABSTRACT

A case of primary thyroid lymphoma demonstrating uptake of ^99mTc-hexakis-2-methoxy isobutyl isonitrile (MIBI) is presented. The ^99mTc-MIBI image more clearly delineated the extent of tumor as demonstrated on CT compared to ^201mTI-chloride and [^99mTc]pertechnetate images. Following two courses of chemotherapy, repeat radionuclide studies and CT scan showed complete resolution of the thyroid tumor. Technetium-99m-MIBI may be useful in the assessment of disease activity and monitoring response to treatment in patients with lymphoma.