HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Hommeyer, S. H. Articles by Eary, J. F. Search for Related Content PubMed PubMed Citation Articles by Hommeyer, S. H. Articles by Eary, J. F.

Skeletal Nonvisualization in a Bone Scan Secondary to Intravenous Etidronate Therapy

Department of Radiology, University of Washington Medical Center, Seattle, Washington

Correspondence: For reprints contact: Janet F. Eary, MD, Associate Professor, Radiology & Pathology, Division of Nuclear Medicine, RC-70, University of Washington Medical Center, 1959 N.E. Pacific, Seattle, WA 98195.

ABSTRACT

Etidronate disodium (EHDP) therapy is often institutede mergently for treatment of hypercalcemia associated with malignancy, and a staging bone scan is part of the evaluation of the patient with extensive metastatic disease. In these patients in whom high dose EHDP therapy has been instituted, uptake of the bone scan agent is markedly diminished. The case presented illustrates this finding: a breast cancer patient who had received two 500-mg intravenous doses of EHDP prior to bone scan staging. No skeletal visualization was present at 3 hr after ^99mTc-MDP injection. Blood-pool activity and uptake in large metastatic sites were observed.

This article has been cited by other articles:

				J. Installe, A. Nzeusseu, A. Bol, G. Depresseux, J.-P. Devogelaer, and M. Lonneux 18F-Fluoride PET for Monitoring Therapeutic Response in Paget's Disease of Bone J. Nucl. Med., October 1, 2005; 46(10): 1650 - 1658. [Abstract] [Full Text] [PDF]

				J. A. Carrasquillo, M. Whatley, V. Dyer, W. D. Figg, and W. Dahut Alendronate Does Not Interfere with 99mTc-Methylene Diphosphonate Bone Scanning J. Nucl. Med., September 1, 2001; 42(9): 1359 - 1363. [Abstract] [Full Text] [PDF]