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Application of a Continuous Ventricular Function Monitor with Miniature Cadmium Telluride Detector to Patients with Coronary Artery Bypass Grafting

Departments of Nuclear Medicine and Surgery (I), Kanazawa University School of Medicine, Kanazawa, Japan

Correspondence: For reprints contact: Junichi Taki, MD, Department of Nuclear Medicine. Kanazawa University School of Medicine, 13-1 Takara-machi, Kanazawa, 920, Japan.

ABSTRACT

A continuous ventricular function monitor with a miniature cadmium telluride detector was evaluated and applied to patients with coronary bypass surgery (CABG). Ejection fraction (EF) at rest and change in EF from rest to exercise and postexercise(Y) measured with the device correlated with that of the gamma camera (X) (Y = 0.86x + 6.8(%), r = 0.87, n = 110, p < 0.001, and Y = 0.96x + 0.4(%), r = 0.90, n = 37, p < 0.001 respectively). Left ventricular function during and after supine ergometer exercise was monitored in 54 patients before and after CABG. The EF change from baseline to peak exercise improved from –5.9% ± 8.9% before CABG to 7.2% ± 7.9% after CABG (p < 0.001). In all patients but two, a rapid EF increase just after exercise over baseline EF was observed. This EF "oeovershoot" during recovery increased from 11.5% ± 6.5% to 16.4% ± 6.0% (p < 0.001) after CABG. The time from the cessation of exercise to EF overshoot decreased from 153 ± 80 sec to 76 ± 49 sec (p < 0.001) after CABG. The continuous ventricular function monitor with a miniature cadmium telluride detector is able to measure EF reliably. Following successful aortocoronary bypass, EF response during exercise improved and the EF overshoot in the recovery phase became faster and higher.

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