HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Yamashita, K. Articles by Konishi, J. Search for Related Content PubMed PubMed Citation Articles by Yamashita, K. Articles by Konishi, J.

Regional Wall Thickening of Left Ventricle Evaluated by Gated Positron Emission Tomography in Relation to Myocardial Perfusion and Glucose Metabolism

Department of Radiology and Nuclear Medicine, Third Division, Department of Internal Medicine, Department of Cardiovascular Surgery, Kyoto University, School of Medicine, Kyoto, Japan

Correspondence: For reprints contact: Keiji Yamashita MD, Dept. of Radiology and Nuclear Medicine, Kyoto University Medical School, Sakyo-ku, Kyoto, 606, Japan.

ABSTRACT

Regional wall thickening was assessed by electrocardiographically gated positron emission tomography (ECG-gated PET) in 26 patients with coronary artery disease. The standardized percent count increase from end-diastole to end-systole (S-percent CI) was calculated as an index of wall thickening. The S-percent CI was 77.8% ± 28.9% in the segments with normal perfusion at rest, 51.9% ± 29.5% in those with mild hypoperfusion, and 32.8% ± 30.9% in those with severe hypoperfusion (p < 0.001, each). Among the segments with resting hypoperfusion, the S-percent CI was 38.9% ± 31.5% in those without stress-induced ischemia and 48.7% ± 30.9% in those with ischemia (p < 0.05). Furthermore, among resting severe hypoperfusion, the S-percent CI was 23.0% ± 23.9% in the segments without fluorine-18-fluorodeoxyglucose (FDG) uptake and 37.8 ± 32.9% in those with FDG uptake (p < 0.05). These results suggest that stress-induced ischemia and FDG accumulation correlated with wall thickening. Thus, quantitative analysis of regional wall thickening seems to be useful for combined analysis of regional function, perfusion and metabolism in coronary patients.

This article has been cited by other articles:

				E. Croteau, F. Benard, J. Cadorette, M.-E. Gauthier, A. Aliaga, M'h. Bentourkia, and R. Lecomte Quantitative Gated PET for the Assessment of Left Ventricular Function in Small Animals J. Nucl. Med., October 1, 2003; 44(10): 1655 - 1661. [Abstract] [Full Text] [PDF]

				C. Rickers, K. Sasse, R. Buchert, H. Stern, J.o. van den Hoff, M. Lubeck, and J. Weil Myocardial viability assessed by positron emission tomography in infants and children after the arterial switch operation and suspected infarction J. Am. Coll. Cardiol., November 1, 2000; 36(5): 1676 - 1683. [Abstract] [Full Text] [PDF]

				A Al-Mohammad, I R Mahy, M Y Norton, G Hillis, J C Patel, P Mikecz, and S Walton Prevalence of hibernating myocardium in patients with severely impaired ischaemic left ventricles Heart, December 1, 1998; 80(6): 559 - 564. [Abstract] [Full Text]

				M.G. Niemeyer, A.F.M. Kuijper, J.G. Meeder, M.J.M. Cramer, A.J.M. Cleophas, E.E. van der Wall, and M. G. Niemeyer Comparison of Thallium Scintigraphy and Positron Emission Tomography Angiology, October 1, 1997; 48(10): 843 - 853. [Abstract] [PDF]