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Microvascular Right-to-Left Pulmonary Shunt Demonstrated by a Radionuclide Method

Cardiovascular Laboratory and Department of Clinical Physiology Nuclear Medicine, Rigshospitalet, University Hospital, Copenhagen, Denmark

Correspondence: For reprints contact: Dr. Erik Kjøller, Medical Department F, Herlev Hospital, University of Copenhagen, DK-2730 Herlev, Denmark.

ABSTRACT

A 37-yr-old man with angiolymphoid hyperplasia (Kimura's syndrome), who had been treated unsuccessfully for suspected asthma, was investigated due to a decrease in arterial oxygen saturation (86%). Right heart catheterization and angiography of the pulmonary artery failed to demonstrate any right-to-left shunts. However, simultaneous scintigraphy over the lungs, kidneys, and head after injection of 150 MBq technetium-99m-labeled macroaggregated albumin i.v. and inhalation of 150 MBq krypton-81m demonstrated a right-to-left shunt in the lungs probably caused by precapillary pulmonary arteriovenous shunts.