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The Journal of Nuclear Medicine Vol. 31 No. 8 1303-1306
© 1990 by Society of Nuclear Medicine
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Improved Detection of Anterior Left Ventricular Aneurysm with Multiharmonic Fourier Analysis

Héric B. Valette, Michel H. Bourguignon, Pascal Merlet, Marie-Claude Grégoire, Dominique Le Guludec, Odile Pascal, Philippe Briandet and André Syrota

Laboratoire d'Explorations Cardiovasculaires, Hôpital de Bicêtre and Service Hospitalier F. Joliot-Commissariat à l'Energie Atomique, Orsay of Sopha Médical, Buc

Correspondence: For reprints contact: H. Valette, Laboratoire d'Explorations Cardiovasculaires, Hopital de Bicêtre, 78 rue du Général LeClerc, 94-275 Bicétre, France.

ABSTRACT

Single and multiharmonic Fourier analysis of LAO 30–45° gated blood-pool studies were performed in a selected group of 30 patients with a left ventricular anterior aneurysm proven by contrast angiography. The sensitivity of the first harmonic phase image for the diagnosis of ventricular aneurysm was 80%. The clear phase shift (>110°) between the normal and the aneurysmal areas was missing in six patients. Peak acceleration images (negative maximum of the second derivative of the Fourier series) were calculated for each pixel with the analytical Fourier formula using two or three harmonics. A clear phase shift (>126°) then appeared in all the patients. This improvement was related to the increased weight of the second and third harmonics in the aneurysmal area when compared to control patients or to patients with dilative cardiomyopathy. Multiharmonic Fourier analysis clearly improved the sensitivity of the diagnosis of anterior left ventricular aneurysm on LAO 30°–45° gated blood-pool images.






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