HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Mulligan, J. S. Articles by Hasbargen, J. A. Search for Related Content PubMed PubMed Citation Articles by Mulligan, J. S. Articles by Hasbargen, J. A.

Methods for Measuring GFR with Technetium-99m-DTPA: An Analysis of Several Common Methods

Department of Radiology, Nuclear Medicine Service, and Department of Medicine, Nephrology Service, Fitzsimons Army Medical Center, Aurora, Colorado

Correspondence: For reprints contact: Peter W. Blue, COL, MC, Nuclear Medicine Service, Fitzsimons Army Medical center, Aurora, Colorado 80045-5001.

ABSTRACT

Several commonly used scintigraphic methods of GFR measurement were evaluated. Forty-three adult patients with a wide range of ages and renal function were studied. The two-sample plasma method of Russell and the urinary method of Jackson were the most accurate methods overall. The one-sample plasma method of Russell, the volume of distribution method of Fawdry, and a terminal slope method were less reliable, especially at low (0–60 ml/min) GFRs. The renal uptake method of Gates correlated poorly to the standards at all GFR levels even when corrected for body surface area or blood volume. The Russell two point and Jackson urinary GFR's can be used as complementary techniques and are recommended as primary methods of scintigraphic GFR determination.

FOOTNOTES

Disclaimer: The opinions and assertions contained here in are the private views of the authors and are not to be construed as reflecting the views of the Army or the Department of Defense.

This article has been cited by other articles:

				N. J. Bird, C. Peters, A. R. Michell, and A. M. Peters Effect of extracellular fluid volume on single-sample measurement of glomerular filtration rate Nephrol. Dial. Transplant., August 19, 2008; (2008) gfn437v1. [Abstract] [Full Text] [PDF]

				Y.-C. Ma, L. Zuo, C.-L. Zhang, M. Wang, R.-F. Wang, and H.-Y. Wang Comparison of 99mTc-DTPA renal dynamic imaging with modified MDRD equation for glomerular filtration rate estimation in Chinese patients in different stages of chronic kidney disease Nephrol. Dial. Transplant., February 1, 2007; 22(2): 417 - 423. [Abstract] [Full Text] [PDF]