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The Journal of Nuclear Medicine Vol. 31 No. 5 617-627
© 1990 by Society of Nuclear Medicine
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Continuous-Slice PENN-PET: A Positron Tomograph with Volume Imaging Capability

Joel S. Karp, Gerd Muehllehner, David A. Mankoff, Caesar E. Ordonez*, John M. Ollinger{dagger}, Margaret E. Daube-Witherspoon{ddagger}, Arthur T. Haigh and Daniel J. Beerbohm

Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania

Correspondence: For reprints contact: Joel S. Karp, PhD, Nuclear Medicine Section, Dept. of Radiology, Hospital of the Univ. of Penn., 3400 Spruce St., Philadelphia, PA 19104.

ABSTRACT

The PENN-PET scanner consists of six hexagonally arranged position-sensitive NaI(Tl) detectors. This design offers high spatial resolution in all three dimensions, high sampling density along all three axes without scanner motion, a large axial acceptance angle, good energy resolution, and good timing resolution. This results in three-dimensional imaging capability with high sensitivity and low scatter and random backgrounds. The spatial resolution is 5.5 mm (FWHM) in all directions near the center. The true sensitivity, for a brain-sized object, is a maximum of 85 kcps/µCi/ml and the scatter fraction is a minimum of 10%, both depending on the lower level energy threshold. The scanner can handle up to 5 mCi in the field of view, at which point the randoms equal the true coincidences and the detectors reach their count rate limit. We have so far acquired [18F]FDG brain studies and cardiac studies, which show the applicability of our scanner for both brain and whole-body imaging. With the results to date, we feel that this design results in a simple yet high performance scanner which is applicable to many types of static and dynamic clinical studies.

FOOTNOTES

* Current address: Franklin McLean Institute, University of Chicago, Chicago, IL.

{dagger} Current address: Biomedical Computing Laboratory, Washington University, St. Louis, MO.

{ddagger} Current address: Nuclear Medicine Department, National Institutes of Health, Washington, DC.




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