HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Palestro, C. J. Articles by Goldsmith, S. J. Search for Related Content PubMed PubMed Citation Articles by Palestro, C. J. Articles by Goldsmith, S. J.

Indium-111-Labeled Leukocyte Scintigraphy in Hemodialysis Access-Site Infection

The Andre Meyer Department of Physics-Nuclear Medicine, Mt. Sinai School of Medicine, Mt. Sinai Medical Center, New York, New York

Correspondence: For reprints contact: Christopher J. Palestro, MD, Mt. Sinai Medical center, Physics-Nuclear Medicine, Box 1141, 1 Gustave L. Levy Pl., New York, NY 10029

ABSTRACT

Bacterial sepsis, a significant complication of chronic hemodialysis, is generally the result of infection at the vascular access site. We retrospectively reviewed the utility of indium-111-(¹¹¹In) labeled autologous leukocyte scintigraphy in 26 patients (30 scans) with synthetic vascular grafts, on chronic hemodialysis, in whom hemodialysis access site infection was a diagnostic consideration. Leukocyte scintigraphy correctly identified all fifteen access-site infections; there was one false-positive study, for an overall sensitivity and specificity of 100% and 93%, respectively. Of particular significance is the fact that in nine (60%) of the fifteen access-site infections, physical examination was normal. Our data indicate that ¹¹¹In-labeled leukocyte scintigraphy is a useful procedure for the diagnosis of hemodialysis access-site infection, and it is especially valuable when physical examination of the access site is normal.

This article has been cited by other articles:

				C. Love and C. J. Palestro Radionuclide Imaging of Infection J. Nucl. Med. Technol., June 1, 2004; 32(2): 47 - 57. [Abstract] [Full Text] [PDF]

				C. J. Palestro, C. Love, G. G. Tronco, and M. B. Tomas Role of Radionuclide Imaging in the Diagnosis of Postoperative Infection RadioGraphics, November 1, 2000; 20(6): 1649 - 1660. [Abstract] [Full Text] [PDF]