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HMPAO-SPECT Imaging Resembling Alzheimer-Type Dementia in Mitochondrial Encephalomyopathy with Lactic Acidosis and Stroke-like Episodes (MELAS)

Departments of Nuclear Medicine and Neurology, University of Bonn, West-Germany

Correspondence: For reprints contact: Frank Grünwald, MD, Clinic for Nuclear Medicine, University of Bonn, Sigmund-Freud-Str. 25, D-5300 Bonn 1, West-Germany.

ABSTRACT

Single-photon emission computed tomography (SPECT) of the brain using hexamethyl propylene amine oxime (HMPAO) was performed in a 37-year-old patient suffering from mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS). Reduced blood flow was observed bilaterally in the parieto-occipital regions (resembling Alzheimer type dementia) and in the right parietal lobe.