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The Journal of Nuclear Medicine Vol. 30 No. 12 2042-2045
© 1989 by Society of Nuclear Medicine
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Captopril Renal Scintigraphy in a Patient with Bilateral Renal Artery Stenosis

Kazuo Itoh, Masahiro Shinohara, Masaki Togashi and Tomohiko Koyanagi

Departments of Nuclear Medicine, Radiology, and Urology, School of Medicine, Hokkaido University, Kita-15 Nishi-7, Kita-ku, Sapporo, 060, Japan

Correspondence: For reprints contact: Kazuo Itoh, MD, Dept. of Nuclear Medicine, School of Medicine, Hokkaido University, Kita-15 Nishi-7, Kita-ku, Sapporo, 060 Japan.

ABSTRACT

A 41-yr-old woman with bilateral renal artery stenosis (RAS) and renovascular hypertension is presented. In this patient, the routine [99mTc]diethylenetriaminepentaacetic acid renal scintigraphy without Captopril was normal and the subsequent study with Captopril showed a marked decrease in glomerular filtration rate of the right kidney alone. Percutaneous transluminal angioplasty of the functionally affected right kidney immediately evoked new renin-dependent hypertension caused by the untreated left RAS. This patient illustrates two major points: (a) as a diagnostic tool, the sensitivity of Captopril renal scintigraphy may be compromised by an inability to detect bilateral RAS, but (b) after angioplasty, it can be useful for evaluating the treated kidney and in revealing contralateral disease that may benefit from angioplasty.







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Copyright © 1989 by the Society of Nuclear Medicine.