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Role of Scintigraphy in Focally Abnormal Sonograms of Fatty Livers

Department of Nuclear Medicine, Division of Gastroenterology, and Division of Ultrasound, Royal Victoria Hospital and McGill University

Correspondence: For reprints contact: Robert Lisbona, MD, Dept. of Nuclear Medicine, Royal Victoria Hospital 687 Pine Ave. West, Montreal, Quebec H3A 1A1 Canada.

ABSTRACT

Fatty infiltration of the liver may cause a range of focal abnormalities on hepatic sonography which may simulate hepatic nodular lesions. Discrete deposits of fat or islands of normal tissue which are uninvolved by fatty infiltration may stand out as potential space-occupying lesions on the sonograms. Twelve patients with such focally abnormal ultrasound images were referred for liver scintigraphy with ¹³³Xe and ^99mTc colloidal SPECT studies to clarify the issue. These examinations helped identify, in nine of 12 patients, the innocent nature of the sonographic abnormalities which were simply related to the fat deposition process. Further, [^99mTc]RBC scans defined the additional pathologic process in three patients in whom actual space-occupying lesions were indeed present in the liver. Scintigraphy has an important role to play in the understanding of focal hepatic ultrasound abnormalities particularly in unsuspected hepatic steatosis.

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