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Evaluation of Cerebral Collateral Circulation by Technetium-99m HM-PAO Brain SPECT During Matas Test: Report of Three Cases

Department of Nuclear Medicine and Department of Neurosurgery, School of Medicine, Kanazawa University, Kanazawa, Japan

Correspondence: For reprints contact: H. Matsuda, MD, Dept. of Nuclear Med. and Dept. of Neurosurgery, School of Medicine, Kanazawa University, 13-1, Takara-machi, Kanazawa City, Ishikawa, 920 Japan.

ABSTRACT

Three cases with cerebral ischemic symptoms and an intracranial aneurysm are presented. Using [^99mTc] hexamethyl-propyleneamine oxime (HM-PAO) single photon emission computed tomography imaging before and during the Matas test, a quantitative measurement method was developed for evaluating brain collateral circulation. The evaluation correlated well with findings of contrast carotid angiography. This noninvasive method seems to be useful for selection of patients for appropriate surgical treatment.