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Technetium-99m-Labeled Red Blood Cells in the Evaluation of Hemangiomas of the Liver in Infants and Children

Division of Nuclear Radiology, Department of Radiology, Childrens Hospital of Los Angeles, and University of Southern California, School of Medicine, Los Angeles, California

Correspondence: For reprints contact: John H. Miller, MD, Head, Div. of Nuclear Radiology, Childrens Hospital of Los Angeles, 4650 Sunset Blvd., Los Angeles, CA 90027.

ABSTRACT

The vascular origin lesions of the liver (capillary hemangioma/infantile hemangioendothelioma) that present in infancy or early childhood often have a typical clinical picture of hepatomegaly and congestive heart failure. These lesions rarely present as asymptomatic hepatomegaly, simulating a primary hepatic malignancy. These lesions may also simulate a primary or secondary hepatic malignancy on cross-sectional imaging or angiography. Scintigraphic evaluations with technetium-99m-labeled red blood cells offers an accurate method of identification of these lesions, and allows differentiation from other common primary or secondary hepatic masses in infancy or childhood. This scintigraphic method may also be used to follow these patients after medical, radiation, or embolization therapy. Experience with seven patients with these tumors is reported and compared with eight children with other primary or secondary liver tumors also evaluated by this method.

FOOTNOTES

Presented in part at the 9th Annual Western Regional Scientific Program of the Society of Nuclear Medicine Meeting, Monterey, CA October 11–14, 1984.